Catalog No: OAAB16873
Size:400ul
Price: $438.00
SKU
OAAB16873
Availability: Domestic: within 1-2 weeks delivery | International: 1-2 weeks
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ACVR2A Antibody - N-terminal region (OAAB16873)

ACVR2A is an activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Datasheets/ManualsPrintable datasheet for OAAB16873
Product Info
Predicted Species ReactivityHuman, Mouse, Bovine, Chicken, Rat, Sheep
Product FormatLiquid. PBS with 0.09% (W/V) sodium azide.
ClonalityPolyclonal
IsotypeIg
HostRabbit
ApplicationWB, IHC-P
Additional InformationCellular Location: Membrane; Single-pass type I membrane protein.
Reconstitution and StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThis ACVR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-29 amino acids from the N-terminal region of human ACVR2A.
PurificationThis antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ConcentrationVaries by lot. See vial for concentration.
Sample Type Confirmation

ACVR2A is strongly supported by BioGPS gene expression data to be expressed in HEK293

Intended UseACVR2A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Application InfoWB: 1:2000
Description
Gene SymbolACVR2A
Alias SymbolsACVR2, ACTRII
NCBI Gene Id92
Protein NameActivin receptor type-2A
Description of TargetACVR2A is an activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Uniprot IDP27037
Protein Accession #NP_001607.1
Molecular Weight57848 Da
  1. What is the species homology for "ACVR2A Antibody - N-terminal region (OAAB16873)"?

    The tested species reactivity for this item is "". This antibody is predicted to have homology to "Human, Mouse, Bovine, Chicken, Rat, Sheep".

  2. How long will it take to receive "ACVR2A Antibody - N-terminal region (OAAB16873)"?

    This item is available "Domestic: within 1-2 weeks delivery | International: 1-2 weeks ".

  3. What buffer format is "ACVR2A Antibody - N-terminal region (OAAB16873)" provided in?

    This item is provided in "Liquid. PBS with 0.09% (W/V) sodium azide. ".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "ACVR2A Antibody - N-terminal region (OAAB16873)"?

    This target may also be called "ACVR2, ACTRII" in publications.

  5. What is the shipping cost for "ACVR2A Antibody - N-terminal region (OAAB16873)"?

    The shipping cost for this item is $40 within the US. Please contact us for specific shipping prices for international orders.

  6. What is the guarantee for "ACVR2A Antibody - N-terminal region (OAAB16873)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "ACVR2A Antibody - N-terminal region (OAAB16873)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "57848 Da".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "ACVR2A Antibody - N-terminal region (OAAB16873)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "ACVR2A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "ACVR2A"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "ACVR2A"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "ACVR2A"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "ACVR2A"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "ACVR2A"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

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